The 63rd United States Colored Infantry Regiment was a U.S.C.T. infantry regiment in the Union Army during the American Civil War. It was reformed from the 9th Louisiana Infantry (African Descent) (which continued to exist as 5th U.S. Colored Heavy Artillery) in March 1864 and served, commanded by Colonel John Eaton, in various garrison posts in Mississippi. It was mustered out on January 9, 1866.