Killers of the Flower Moon may refer to:
- Killers of the Flower Moon (book), a 2017 nonfiction book by American journalist David Grann about the Osage murders
- Killers of the Flower Moon (film), a 2023 American film directed by Martin Scorsese, based on the book
- Killers of the Flower Moon (soundtrack), the soundtrack album composed by Robbie Robertson for the film