Major General James G. Blunt

AS-19 is a substance which acts as a potent agonist at the 5-HT7 receptor, with an IC50 of 0.83 nM. It reverses the amnesia induced by drugs such as scopolamine and dizocilpine and improves long-term memory acquisition, but inhibits short-term memory formation.[1][2]

See also

References

  1. ^ Meneses A, Perez-Garcia G, Liy-Salmeron G, Flores-Galvez D, Castillo C, Castillo E (December 2008). "The effects of the 5-HT(6) receptor agonist EMD and the 5-HT(7) receptor agonist AS19 on memory formation". Behavioural Brain Research. 195 (1): 112–9. doi:10.1016/j.bbr.2007.11.023. PMID 18191236. S2CID 144901859.
  2. ^ Perez-García G, Meneses A (December 2008). "Ex vivo study of 5-HT(1A) and 5-HT(7) receptor agonists and antagonists on cAMP accumulation during memory formation and amnesia". Behavioural Brain Research. 195 (1): 139–46. doi:10.1016/j.bbr.2008.07.033. PMID 18723050. S2CID 140204255.
source: https://en.wikipedia.org/wiki/AS-19_(drug)