Major General James G. Blunt

Piroheptine (brand name Trimol) is an anticholinergic and antihistamine used as an antiparkinsonian agent.

Piroheptine was observed to prevent the reuptake of dopamine and is therefore a DRI.[1][2]

Piroheptine comes from a family of drugs that includes pridefine and etifelmine.

References

  1. ^ Saitoh T (February 1988). "Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity in mouse brain by piroheptine and trihexyphenidyl". Journal of the Neurological Sciences. 83 (2–3): 161–166. doi:10.1016/0022-510X(88)90065-2. PMID 3258627. S2CID 25230405.
  2. ^ Ohashi T, Akita H, Tamura T, Noda K, Honda F (June 1972). "Effect of piroheptine, a new antiparkinson drug, on dopamine uptake into synaptosomes from corpus striatum of rat brain". Arzneimittel-Forschung. 22 (6): 966–972. PMID 5068358.
source: https://en.wikipedia.org/wiki/Piroheptine