Major General James G. Blunt

SB-366791 is a drug which acts as a potent and selective blocker of the TRPV1 ion channel. It has analgesic effects in animal studies, and is used in research into pain and inflammation.^[1]^[2]^[3]

References

^ Dell H (December 2003). "New compound fires up pain research". Drug Discovery Today. 8 (23): 1053. doi:10.1016/s1359-6446(03)02928-3. PMID 14693457.
^ Ma SX, Kim HC, Lee SY, Jang CG (December 2018). "TRPV1 modulates morphine self-administration via activation of the CaMKII-CREB pathway in the nucleus accumbens". Neurochemistry International. 121: 1–7. doi:10.1016/j.neuint.2018.10.009. PMID 30292787. S2CID 52929149.
^ Uchytilova E, Spicarova D, Palecek J (April 2021). "Hypersensitivity Induced by Intrathecal Bradykinin Administration Is Enhanced by N-oleoyldopamine (OLDA) and Prevented by TRPV1 Antagonist". International Journal of Molecular Sciences. 22 (7): 3712. doi:10.3390/ijms22073712. PMC 8038144. PMID 33918267.

[1] Dell H (December 2003). "New compound fires up pain research". Drug Discovery Today. 8 (23): 1053. doi:10.1016/s1359-6446(03)02928-3. PMID 14693457.

[2] Ma SX, Kim HC, Lee SY, Jang CG (December 2018). "TRPV1 modulates morphine self-administration via activation of the CaMKII-CREB pathway in the nucleus accumbens". Neurochemistry International. 121: 1–7. doi:10.1016/j.neuint.2018.10.009. PMID 30292787. S2CID 52929149.

[3] Uchytilova E, Spicarova D, Palecek J (April 2021). "Hypersensitivity Induced by Intrathecal Bradykinin Administration Is Enhanced by N-oleoyldopamine (OLDA) and Prevented by TRPV1 Antagonist". International Journal of Molecular Sciences. 22 (7): 3712. doi:10.3390/ijms22073712. PMC 8038144. PMID 33918267.

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[2]

[3]

See also

References