James Williams may refer to:
Entertainment
- James J. Williams (1853–1926), English photographer
- James Dixon Williams (1877–1934), American film producer
- James Williams (musician) (1951–2004), American jazz pianist
- James D-Train Williams (born 1962), American singer, songwriter and musician
- James K. Williams, Liberian rapper
- J. R. Williams (James Robert Williams), Canadian cartoonist
Military
- James Williams (Revolutionary War) (1740–1780), colonel from South Carolina
- James Monroe Williams (1833–1907), American Civil War soldier
- James Howard Williams (1897–1958), British soldier and elephant expert in Burma
- James E. Williams (1930–1999), Medal of Honor in the U.S. Navy
- James A. Williams (1932–2017), U.S. Army general
- James L. Williams, commanding general of the 4th Marine Division
Politics
- James Wray Williams (1792–1842), U.S. Representative from Maryland
- James Williams (ambassador) (1796–1869), to Ottoman Empire
- James D. Williams (1808–1880), U.S. Representative from Indiana
- James Williams (Ohio politician) (1822–1892), Republican
- James Williams (Delaware politician) (1825–1899), U.S. Representative
- James E. Williams (Atlanta mayor) (1826–1900), Atlanta mayor after the Civil War
- James E. Williams (East St. Louis mayor)
- James M. Williams (1850–1909), Ohio House and Ohio Senate
- James R. Williams (politician) (1850–1923), U.S. Representative from Illinois
- James R. Williams (lawyer) (1936–2020), candidate for lieutenant governor of Ohio
- James D. Williams (Pennsylvania politician) (1943–1985), Pennsylvania House
- James Edwin Williams (1856–1917), British trade unionist
- James Williams (labor leader), American president of painters' union
- James A. Williams Jr., American labor union leader
- James Harrison Williams, member of the Iowa House of Representatives
Religion
- James Williams (priest, died 1872) (1790–1872), Welsh clergyman
- James Williams (bishop) (1825–1892), Canadian Church of England
- James Williams (archdeacon of Ardfert) (died 1724)
- James Williams (archdeacon of Wrexham)
- James Kendrick Williams (born 1936), American Catholic bishop
Sports
American football
- James Williams (end) (1928–2015), Rice University
- James Williams (cornerback) (born 1967), American football cornerback
- James Williams (safety) (born 2003), American football safety
- James Williams (wide receiver) (born 1978), American football wide receiver
- James O. Williams (born 1968), American football offensive tackle
- James Williams (linebacker) (born 1968), American football linebacker
- Jamie Williams (American football) (born 1960), NFL tight end
Association football
- James Williams (Welsh footballer) (1885–1916)
- James Williams (Australian footballer) (born 1937)
- James Williams-Richardson (born 1988), Anguillan international footballer
- James Williams (Irish footballer)
- Jimmy Williams (footballer, born 1982), English footballer
Other sports
- James Williams (baseball), co-owner of the Cincinnati Reds baseball team 1981–1984
- James Williams (basketball) (born 1979), American
- James Williams (British fencer) (born 1966)
- James Williams (cricketer) (born 1973), Welsh
- James Williams (field hockey) (1878–1929), British
- Jimmy Williams (coach) (James Bernard Williams, 1926–2016), minor league baseball manager
- Fly Williams (James Williams, born 1953), American basketball player
- James Leighman Williams (born 1985), American fencer
- Jimy Williams (1943–2024), American baseballer
Other uses
- James Miller Williams (1818–1890), Canadian oil businessman
- James Nelson Williams (1837–1915), New Zealand runholder, orchardist and entrepreneur
- James Leon Williams (1852–1932), American dental researcher
- James Steele Williams (1896–1957), American paleontologist
- James Arthur Williams (1930–1990), American antiques dealer
- James Wilson Williams (born 1982), American academic
- James Oladipo Williams (died 1999), Nigerian jurist and judge
- James F. Williams, American librarian, University of Colorado
- James H. Williams Jr., American mechanical engineer, MIT
- Jamie Williams, president of the Wilderness Society
- USS James E. Williams, an Arleigh Burke-class destroyer in the United States Navy