Colonel William A. Phillips

Glutarimide is the organic compound with the formula (CH2)3(CO)2NH. It is a white solid. The compound forms upon dehydration of the amide of glutaric acid.[2]

Glutarimide is sometimes called 2,6-piperidinedione. It is the core of a variety of drugs, including thalidomide, a medication used to treat multiple myeloma[3] and leprosy,[4] and cycloheximide, a potent inhibitor of protein synthesis.[5]

References

  1. ^ Glutarimide - Sigma-Aldrich
  2. ^ Paris, G.; Berlinguet, L.; Gaudry, R.; English, Jr., J.; Dayan, J. E. (1957). "Glutaric Acid and Glutarimide". Organic Syntheses. 37: 47. doi:10.15227/orgsyn.037.0047.
  3. ^ "A to Z List of Cancer Drugs: Thalidomide". National Cancer Institute. Retrieved 20 September 2021.
  4. ^ Stolberg SG (17 July 1998). "Thalidomide Approved to Treat Leprosy, With Other Uses Seen". New York Times. Retrieved 20 September 2021.
  5. ^ Sisler, Hugh D.; Siegel, Malcolm R. (1967). "Cycloheximide and Other Glutarimide Antibiotics". Mechanism of Action. pp. 283–307. doi:10.1007/978-3-642-46051-7_21. ISBN 978-3-642-46053-1.
source: https://en.wikipedia.org/wiki/Piperidinedione