| Elections in Mississippi |
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The 2000 United States Senate election in Mississippi was held on November 7, 2000. Incumbent Republican U.S. Senator Trent Lott won re-election to a third term.
Major candidates
Democratic
- Troy Brown, perennial candidate
Republican
- Trent Lott, incumbent U.S. Senator first elected in 1988
Results
| Party | Candidate | Votes | % | ±% | |
|---|---|---|---|---|---|
| Republican | Trent Lott | 654,941 | 65.88% | -2.92% | |
| Democratic | Troy D. Brown | 314,090 | 31.59% | +0.39% | |
| Independent | Jim Giles | 9,344 | 0.94% | ||
| Libertarian | Lewis Napper | 8,454 | 0.85% | ||
| Reform | Shawn O'Hara | 7,315 | 0.74% | ||
| Republican hold | Swing | ||||
Counties that flipped from Republican to Democratic
- Quitman (Largest city: Lambert)
- Sharkey (Largest city: Rolling Fork)
- Issaquena (Largest city: Mayersville)
- Marshall (Largest city: Holly Springs)
- Noxubee (Largest city: Macon)
- Bolivar (Largest city: Cleveland)
- Sunflower (Largest city: Indianola)
- LeFlore (Largest city: Greenwood)