Sebastián Lerdo de Tejada was president of Mexico from 1872 to 1876.
Lerdo de Tejada may also refer to:
- People
- Miguel Lerdo de Tejada (1812–1861), Mexican politician, elder brother of the above
- Miguel Lerdo de Tejada (composer) (1869–1941)
- Places named for Sebastián Lerdo de Tejada
- Lerdo de Tejada, Veracruz, a city and municipality
- Lerdo de Tejada metro station, on the Monterrey Metro