Robert E. Lee High School may refer to:
Schools currently named Robert E. Lee High School
Schools formerly named Robert E. Lee High School
- John R. Lewis High School (Fairfax County, Virginia)
- Liberty Magnet High School (Baton Rouge, Louisiana)
- Legacy of Educational Excellence High School (San Antonio, Texas)
- Margaret Long Wisdom High School (Houston, Texas)
- Dr. Percy L. Julian High School (Montgomery, Alabama)
- Staunton High School (Staunton, Virginia)
- Legacy High School (Midland, Texas)
- Tyler Legacy High School (Tyler, Texas)
- Lee Academy (South Carolina) (Bishopville, South Carolina)
- Upson-Lee High School, (Thomaston, Georgia)
- Riverside High School (Florida) (Jacksonville, Florida)