USS Minneapolis has been the name of more than one United States Navy ship, and may refer to:
- USS Minneapolis (C-13), was a cruiser in service from 1894 to 1921
- USS Minneapolis (CA-36), was a heavy cruiser commissioned in 1934, in heavy action throughout the Pacific War, and decommissioned in 1947
- USS Minneapolis–Saint Paul (SSN-708), the twenty-first Los Angeles-class submarine, in commission from 1984 to 2008
- USS Minneapolis-Saint Paul (LCS-21) is a Freedom-class littoral combat ship