Battle of Honey Springs

CGS-12066A is a drug which acts as a potent and selective agonist for the 5-HT1B receptor with lower affinity for the three 5-HT2 receptor subtypes.[1][2] It is used for studying the role of the 5-HT1B receptor in various processes including perception of pain and the sleep-wake cycle.[3][4]

References

  1. ^ Knight AR, Misra A, Quirk K, Benwell K, Revell D, Kennett G, Bickerdike M (August 2004). "Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors". Naunyn-Schmiedeberg's Archives of Pharmacology. 370 (2): 114–23. doi:10.1007/s00210-004-0951-4. PMID 15322733. S2CID 8938111.
  2. ^ Jeong HS, Jang MJ, Park JS (March 2005). "Effects of CGS-12066A on medial vestibular nuclear neurons". Brain Research. 1038 (1): 118–21. doi:10.1016/j.brainres.2005.01.025. PMID 15748881. S2CID 22734919.
  3. ^ Monti JM, Jantos H (2008). "The roles of dopamine and serotonin, and of their receptors, in regulating sleep and waking". Serotonin–Dopamine Interaction: Experimental Evidence and Therapeutic Relevance. Progress in Brain Research. Vol. 172. pp. 625–46. doi:10.1016/S0079-6123(08)00929-1. ISBN 9780444532350. PMID 18772053.
  4. ^ Granados-Soto V, Argüelles CF, Rocha-González HI, Godínez-Chaparro B, Flores-Murrieta FJ, Villalón CM (January 2010). "The role of peripheral 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E and 5-HT1F serotonergic receptors in the reduction of nociception in rats". Neuroscience. 165 (2): 561–8. doi:10.1016/j.neuroscience.2009.10.020. PMID 19837141. S2CID 195684404.


source: https://en.wikipedia.org/wiki/CGS-12066A