Ethenzamide (2-ethoxybenzamide) is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains.[1][2] It is also an ingredient in numerous cold medications and many prescription analgesics.[citation needed] It is used as an over-the-counter drug in Japan, often in combination with caffeine and acetaminophen, where it is marketed for uses including toothache, menstrual cramps, headache, and fever.[3]
It is metabolized in vivo into salicylamide.[4]
References
- ^ Darias V, Bravo L, Abdallah SS, Sánchez Mateo CC, Expósito-Orta MA, Lissavetsky J, Manzanares J (February 1992). "Synthesis and preliminary pharmacological study of thiophene analogues of the antipyretic and analgesic agent ethenzamide". Archiv der Pharmazie. 325 (2): 83–7. doi:10.1002/ardp.19923250206. PMID 1605721. S2CID 28098596.
- ^ Wang PJ, Guo HR (2004). "Frequent analgesics consumption in migraineurs: Comparison between chronic and episodic migraineurs". The Journal of Headache and Pain. 5 (1): 30–35. doi:10.1007/s10194-004-0065-x. PMC 3452147.
- ^ "OTC Pain Relief Medicine in Japan". Life Abroad. Retrieved March 22, 2021.
- ^ "エテンザミド" [Ethenzamide] (in Japanese). Retrieved March 22, 2021.
| pyrazolones / pyrazolidines | |
|---|---|
| salicylates | |
| acetic acid derivatives and related substances | |
| oxicams | |
| propionic acid derivatives (profens) |
|
| n-arylanthranilic acids (fenamates) | |
| COX-2 inhibitors (coxibs) | |
| other | |
| NSAID combinations | |
Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use. | |
