Battle of Honey Springs

γ-Oryzanol is a mixture of lipids derived from rice (Oryza sativa).[1] γ-Oryzanol occurs mainly in the fat fraction of rice bran and rice bran oil.

Originally thought to be a single chemical compound,[2] it is now known to be a mixture of ferulic acid esters of phytosterols and triterpenoids, particularly cycloartenyl ferulate, 24-methylenecycloartanyl ferulate, and campesteryl ferulate,[3] which together account for 80% of γ-oryzanol.[4]

Composition

Major constituents of γ-oryzanol
Name(s) Chemical structure Molecular formula CAS number
• Cycloartenyl ferulate
• Oryzanol A 		C40H58O4 21238-33-5
• 24-Methylenecycloartanyl ferulate
• Oryzanol C 		C41H60O4 469-36-3
• Campesteryl ferulate C38H56O4 20972-07-0

Minor constituents include Δ7-stigmastenyl ferulate, stigmasteryl ferulate, Δ7-campestenyl ferulate, Δ7-sitostenyl ferulate, sitosteryl ferulate, compestanyl ferulate, and sitostanyl ferulate.[3]

Uses

γ-Oryzanol has been used in Japan for menopausal symptoms, mild anxiety, stomach upset, and high cholesterol.[5] It is still approved in China for this use.[6] However, there is no meaningful evidence supporting its efficacy for these purposes.[5]

In the United States, it is sold as a sports supplement, but existing research does not support the belief that it has any ergogenic or testosterone-raising effects.[7]

References

  1. ^ R. M. Saunders (1985). "Rice bran: Composition and potential food uses". Food Reviews International. 1 (3): 465–495. doi:10.1080/87559128509540780.
  2. ^ Kaimal, T. B. N. (1999). "γ-Oryzanol from ricebran oil". J Oil Technol Assoc India. 31: 83–93.
  3. ^ a b Zhimin Xu and J. Samuel Godber (1999). "Purification and Identification of Components of γ-Oryzanol in Rice Bran Oil". J. Agric. Food Chem. 47 (7): 2724–2728. doi:10.1021/jf981175j. PMID 10552553.
  4. ^ Xu Zhimin, Godber J S & Xu Z. "Antioxidant activities of major components of gamma-oryzanol from rice bran using a linolenic acid model". J Am Oil Chem Soc. 78 (2001): 465–469.
  5. ^ a b "Gamma Oryzinol". Winchester Hospital.
  6. ^ "National Drug Standard for 谷维素片 / Oryzanol Tablets (DRAFT)" (PDF). 国家食品药品监督管理总局. Archived from the original (PDF) on 29 July 2018. Retrieved 29 July 2018.
  7. ^ Melvin Williams (2006). "Dietary Supplements and Sports Performance: Herbals". Journal of the International Society of Sports Nutrition. 3 (1): 1–6. doi:10.1186/1550-2783-3-1-1. PMC 2129138. PMID 18500959.
source: https://en.wikipedia.org/wiki/Gamma-oryzanol