Battle of Honey Springs

WAY-208466 is a potent and highly selective full agonist of the 5-HT6 receptor.[1] It increases GABA levels in the cerebral cortex and tolerance does not appear to occur to this action upon chronic administration.[1] Animal studies have shown that WAY-208466 produces antidepressant and anxiolytic effects in rodents and it may also be useful in the treatment of obsessive-compulsive disorder.[1][2]

See also

References

  1. ^ a b c Schechter LE, Lin Q, Smith DL, et al. (May 2008). "Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466". Neuropsychopharmacology. 33 (6): 1323–35. doi:10.1038/sj.npp.1301503. PMID 17625499.
  2. ^ Carr GV, Schechter LE, Lucki I (March 2010). "Antidepressant and anxiolytic effects of selective 5-HT(6) receptor agonists in rats". Psychopharmacology. 213 (2–3): 499–507. doi:10.1007/s00213-010-1798-7. PMC 2910165. PMID 20217056.
source: https://en.wikipedia.org/wiki/WAY-208466