The Little River is a tributary of the Canadian River, 90 miles (140 km) long, in central Oklahoma, United States. Via the Canadian and Arkansas rivers, it is part of the watershed of the Mississippi River.
The Little River rises in Moore in northwestern Cleveland County and flows generally southeastwardly through Pottawatomie, Seminole and Hughes counties. It joins the Canadian River about 5 miles (8 km) south of Holdenville. In Cleveland County, the river is dammed to form Lake Thunderbird. Downstream of the lake, several sections of the river have been straightened and channelized.
At , the river has a mean annual discharge of 360 cubic feet per second (10 cubic metres per second).
- Columbia Gazetteer of North America entry
- DeLorme (2003). Oklahoma Atlas & Gazetteer. Yarmouth, Maine: DeLorme. ISBN 0-89933-283-8.
- U.S. Geological Survey Geographic Names Information System: Little River
- Pilot Study of Natural Attenuation of Arsenic in Well Water Discharged to the Little River above Lake Thunderbird, Norman, Oklahoma, 2012 United States Geological Survey