Battle of Backbone Mountain

JTE 7-31 is a selective cannabinoid receptor agonist invented by Japan Tobacco.[1][2] It is a reasonably highly selective CB2 agonist, but still retains appreciable affinity at CB1, with a Ki of 0.088nM at CB2 vs 11nM at CB1.[3]

Legality

JTE 7-31 is illegal in Alabama.[4]

See also

References

  1. ^ WO patent 1997/029079, Inaba T, Kaya T, Iwamura H, "Novel compounds and pharmaceutical use thereof", granted 1997-14-08 
  2. ^ US patent 6017919, Inaba T, Kaya T, Iwamura H, "Compounds and pharmaceutical use thereof", granted 2000-01-25 
  3. ^ Han S, Zhang FF, Qian HY, Chen LL, Pu JB, Xie X, Chen JZ (March 2015). "Design, syntheses, structure-activity relationships and docking studies of coumarin derivatives as novel selective ligands for the CB2 receptor". European Journal of Medicinal Chemistry. 93: 16–32. doi:10.1016/j.ejmech.2015.01.054. PMID 25644673.
  4. ^ "Alabama Senate Bill SB 333: Controlled Substances" (PDF).

External links


source: https://en.wikipedia.org/wiki/JTE_7-31